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Granulocyte Macrophage Colony Stimulating Factor-Pipeline Review H2 2018

 



(Medical-NewsWire.com, November 23, 2018 ) Granulocyte Macrophage Colony Stimulating Factor (GMCSF or Colony Stimulating Factor or CSF or Molgramostin or Sargramostim or CSF2)-Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a glycoprotein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts. It stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.



Granulocyte Macrophage Colony Stimulating Factor (GMCSF or Colony Stimulating Factor or CSF or Molgramostin or Sargramostim or CSF2) pipeline Target constitutes close to 20 molecules. Out of which approximately 19 molecules are developed by companies and remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, Preclinical, Discovery and Unknown stages are 1, 9, 3, 3, 2 and 1 respectively. Similarly, the universities portfolio in Phase II stages comprises 1 molecules, respectively.



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Report covers products from therapy areas Oncology, Immunology, Central Nervous System, Respiratory, Musculoskeletal Disorders and Undisclosed which include indications Breast Cancer, Solid Tumor, Melanoma, Rheumatoid Arthritis, Hepatocellular Carcinoma, Metastatic Breast Cancer, Metastatic Colorectal Cancer, Metastatic Renal Cell Carcinoma, Muscle Invasive Bladder Cancer (MIBC), Soft Tissue Sarcoma, Squamous Cell Carcinoma, Anaplastic Large Cell Lymphoma (ALCL), Ankylosing Spondylitis (Bekhterev's Disease), Axial Spondyloarthritis, Basal Cell Carcinoma (Basal Cell Epithelioma), Colon Carcinoma, Colorectal Cancer, Cutaneous T-Cell Lymphoma, Esophageal Cancer, Extramammary Paget Disease (EMPD), Gastric Cancer, Glioblastoma Multiforme (GBM), Juvenile Myelomonocytic Leukemia (JMML), Kidney Cancer (Renal Cell Cancer), Leukemias, Liver Cancer, Lung Adenocarcinoma, Lung Cancer, Lung Disease, Lymphoma, Malignant Pleural Effusion, Merkel Cell Carcinoma, Metastatic Adenocarcinoma of The Pancreas, Metastatic Hepatocellular Carcinoma (HCC), Metastatic Liver Cancer, Metastatic Melanoma, Multiple Myeloma (Kahler Disease), Multiple Sclerosis, Mycosis Fungoides, Natural Killer Cell Lymphomas, Neurotoxicity Syndromes, Non Muscle Invasive Bladder Cancer (NMIBC) (Superficial Bladder Cancer), Non-Small Cell Lung Cancer, Nonmelanomatous Skin Cancer, Oral Cavity (Mouth) Cancer, Ovarian Cancer, Pancreatic Cancer, Pancreatic Ductal Adenocarcinoma, Peripheral T-Cell Lymphomas (PTCL), Prostate Cancer, Recurrent Head And Neck Cancer Squamous Cell Carcinoma, Sezary Syndrome and Unspecified.



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