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(Medical-NewsWire.com, May 21, 2018 ) Colorectal cancer: a new cancer in the market
Global colorectal cancer market: Colorectal cancer is also known as bowel cancer. It refers to the abnormal growth of the cells in colon and rectum due to cancer. Colorectal cancer starts either in the colon and rectum. Cancer starts as a polyp in the inner wall of the colon or rectum. These polyps can be benign or malignant. Some of the risk factors that can cause colorectal cancer are lifestyle changes, old age, genetic disorders, family history, and inflammatory bowel disease. Some of the symptoms of colorectal cancer are blood in stool, decrease in appetite, constipation, weight loss, nausea, bloating, and pelvic pain.
Global colorectal cancer market is driven by some of the major factors such as increasing prevalence of colorectal cancer, technological advancements in the cancer therapy, aging population, and raise in consumer awareness about colorectal cancers. However, high costs of screening tests and drugs, lack of knowledge are some of the restraints that are hampering the growth of the global colorectal cancer drugs market.
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The global colorectal cancer drugs market is divided into following categories-
1. Therapy
• Adjuvant Chemotherapy
• Palliative Chemotherapy
• Immunotherapy
• Neo Adjuvant Chemotherapy
2. Drug type
• Capecitabine
• Irinotecan
• Fluorouracil
• Trifluridine/tipiracil
• Oxaliplatin
• Others
3. End-users
Retail, hospital and online pharmacies.
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And lastly, on the basis of geographical regions, global colorectal cancer treatment market is segmented into five key regions such as Latin America, North America, Asia-Pacific, Europe and the Middle East and Africa. North America expected to grow at significant rate in colorectal cancer drugs market owing to the growing incidence of colorectal cancer and widespread awareness about early diagnosis and treatment of colorectal cancer. Asia Pacific region expected to have rapid growth in the market owing to huge population densities and high incidence of colorectal cancer in countries such as India and China. Some of the key players in the colorectal cancer drugs market are Amgen Inc. (U.S), Bristol-Myers Squibb Company (U.S.), F. Hoffmann-La Roche Ltd. (Switzerland), Bayer AG (Germany), Merck & Co., Inc. (U.S.), and Sanofi (France) to name a few. For e.g. in Aug 2016, Sanofi’s Zaltrap received USFDA approval to use with FOLFIRI to treat adult patients having colorectal cancer. Similarly, in 2014, the USFDA approved for Amgen’s Vectibix (panitumumab) for use in combination with FOLFOX, to treat metastatic colorectal cancer. And in 2013, Genentech received USFDA approval for the first generic version of Xeloda, to treat cancer of the colorectal cancer.
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Some of the commonly used drugs for the treatment regimens include:
• 5-FU
• Capecitabine, an oral form of 5-FU
• 5-FU with leucovorin (Wellcovorin), a vitamin that improves the effectiveness of 5-FU
• FOLFIRI: 5-FU with leucovorin and irinotecan
• FOLFOX: 5-FU with leucovorin and oxaliplatin
• Irinotecan alone
• XELOX/CAPEOX: Capecitabine with oxaliplatin
• XELIRI/CAPIRI: Capecitabine with irinotecan
Colorectal cancer is the third most common cancer in the world. Huge government initiatives taken by the nations are booming up the growth of the colorectal cancer drugs treatment market globally. Biologics such as Zaltrap (Ziv-Aflibercept), Erbitux (Cetuximab), Avastin (Bevacizumab) are using rapidly for the treatment for colorectal cancer that are used as a targeted therapy and they acts only on the malignant cells. Market players in the colorectal cancer drugs market forming strategic alliances and partnerships to increase their market share.
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