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(Medical-NewsWire.com, March 20, 2015 ) Fovista is a first-in-class anti-platelet-derived growth factor (anti-PDGF) agent being developed by Ophthotech for the treatment of wAMD as a combination therapy with an anti-VEGF drug, such as Lucentis, Avastin, or Eylea. The company is currently conducting a Phase III clinical program consisting of three large trials that are investigating the efficacy of Fovista combination therapy with anti-VEGF agents in comparison with anti-VEGF monotherapy, which is the current standard of care across the 7MM.
Macular Edema is a condition where fluid accumulates on the macula, leading to vision impairment or in severe cases even vision loss. The three main types of ME are diabetic macular edema (DME), and macular edema following either a central or branch retinal vein occlusion (ME-CRVO and ME-BRVO). Age-related macular degeneration (AMD) is a painless eye condition which leads to gradual, irreversible, loss of central vision, and is one of the leading causes of blindness among people aged 50 and over in the developed world. Currently the ME and AMD markets are dominated by the use of anti-VEGF monotherapy, however, in recent years, corticosteroid implants have been reaching the ME market which could challenge the stronghold these drugs have in this sector.
The AMD market will see the arrival of the first therapies to treat dry AMD, fulfilling a huge unmet need in the management of this retinal disease, and these first-in-class therapies will strongly drive the market growth over the next ten years. The launch of wet AMD adjunctive therapies will also see a significant change in the treatment of AMD patients and have a positive impact on the market growth.
Scope:
• Overview of Macular Edema and Macular Degeneration, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
• Detailed information on Fovista including product description, safety and efficacy profiles as well as a SWOT analysis.
• Sales forecast for Fovista for the top country from 2013 to 2023.
• Sales information covered for the US, France, Germany, Italy, Spain, UK and Japan.
Order a Purchase copy of this report at http://www.rnrmarketresearch.com/contacts/purchase?rname=312784 . (This is a premium report priced at US$3495 for a single user License.)
Reasons to Buy:
• Understand and capitalize by identifying products that are most likely to ensure a robust return.
• Stay ahead of the competition by understanding the changing competitive landscape for Macular Edema and Macular Degeneration.
• Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential.
• Make more informed business decisions from insightful and in-depth analysis of Fovista performance.
• Obtain sales forecast for Fovista from 2013-2023 in top 7 countries (the US, France, Germany, Italy, Spain, UK and Japan).
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Table of Contents:
1 Table of Contents 6
1.1 List of Tables 9
1.2 List of Figures 10
2 Introduction 11
2.1 Related Reports 12
3 Disease Overview 14
3.1 Macular Degeneration Overview 14
3.1.1 Etiology and Pathophysiology 16
3.1.2 Classification 20
3.1.3 Symptoms and Diagnosis 22
3.2 Macular Edema Overview 25
3.2.1 Etiology and Pathophysiology 26
3.2.2 Classification 29
3.2.3 Symptoms and Diagnosis 30
4 Disease Management 33
4.1 Diagnosis and Treatment Overview 33
4.1.1 Macular Edema Diagnosis 33
4.1.2 Macular Degeneration Diagnosis 33
4.1.3 Treatment Guidelines and Leading Prescribed Drugs 34
4.1.4 Clinical Practice 36
5 Competitive Assessment 50
5.1 Overview 50
6 Unmet Need and Opportunity 52
6.1 Overview 52
6.2 Treatment for Dry AMD 53
6.2.1 Unmet Need 53
6.2.2 Gap Analysis 55
6.2.3 Opportunity 57
6.3 Longer-Acting Anti-VEGF Drug Therapy 59
6.3.1 Unmet Need 59
6.3.2 Gap Analysis 61
6.3.3 Opportunity 61
6.4 Increased Efficacy of Anti-VEGF Therapy for wAMD 62
6.4.1 Unmet Need 62
6.4.2 Gap Analysis 63
6.4.3 Opportunity 64
6.5 Less Invasive Drug Formulations 64
6.5.1 Unmet Need 64
6.5.2 Gap Analysis 65
6.5.3 Opportunity 66
6.6 Awareness and Earlier Patient Diagnosis 67
6.6.1 Unmet Need 67
6.6.2 Gap Analysis 68
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Source: EmailWire.Com 
Source: EmailWire.com
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