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(Medical-NewsWire.com, April 23, 2016 ) The APAC Systemic Psoriasis Therapeutics Treatment Industry Report estimates the market size for 2014, along with forecasts until 2021. It also covers disease epidemiology, treatment algorithms, treatment use patterns, in-depth analysis of pipeline molecules, clinical trial failure rates, and analysis of recent deals. It is built using data and information sourced from proprietary databases, primary and secondary research, and in-house analysis carried out by GBI Research's team of industry experts. In 2014, the value of the psoriasis therapeutics market in APAC amounted to an estimated $435m, and it is forecast to grow at a Compound Annual Growth Rate (CAGR) of 8.4% between 2014 and 2021 to reach $773m. The psoriasis treatment landscape is a particularly complex one. More than 80% of patients fall into the mild-or-moderate category, for which the first line of treatment is topical drugs, phototherapy, or a combination.
Other Key Points in Report:
The report analyzes treatment use patterns, market characterization, the pipeline, and key licensing and co-development deals for psoriasis in the APAC markets of China, India, Japan, and Australia.The report includes-
-A brief introduction to psoriasis, including pathophysiology, etiology, diagnosis, and treatment algorithms
-In-depth analysis of currently marketed drugs, including analysis of safety, efficacy, treatment patterns, and strengths/weaknesses, along with a heat map comparing them in terms of safety and efficacy
-A comprehensive review of the pipeline for psoriasis, including individual analysis of a number of late-stage pipeline drugs likely to enter the market during the forecast period; the pipeline is further analyzed on the basis of phase distribution, molecule type, program type, mechanism of action, and molecular target
-Additional in-depth analysis of pipeline drug clinical trials by phase, trial size, trial duration, and program failure rate for each molecule type
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Table of Content: An Overview
2 Introduction 10
2.1 Symptoms 11
2.1.1 Skin Manifestations 11
2.1.2 Psychological Impact 11
2.2 Etiology, Co-morbidities and Risk Factors 11
2.2.1 Genetics 11
2.2.2 Psoriatic Arthritis 11
2.2.3 Mental Health Disorders 12
2.2.4 Metabolic Syndrome, Smoking, Diet and Alcohol Consumption 12
2.2.5 Infections 12
2.2.6 Köebner Phenomenon 13
2.2.7 Other Immune-Mediated Diseases 13
2.3 Pathophysiology 13
2.4 Diagnosis 14
2.5 Epidemiology 14
2.6 Treatment and Management 15
2.6.1 Pharmacological Therapies 16
2.6.2 Non-pharmacological Therapies 17
2.6.3 Combination and Rotational Therapies 18
2.6.4 Quality of Life Assessments 18
2.6.5 Summary 18
3 Marketed Products 19
3.1 Overview 19
3.2 Methotrexate-Based Products 19
3.3 Sandimmune/Neoral (cyclosporine/modified cyclosporin)-Novartis 20
3.4 Humira (adalimumab)-AbbVie 21
3.5 Enbrel (etanercept)-Amgen 23
3.6 Remicade (infliximab)-Janssen Biotech 25
3.7 Stelara (ustekinumab)-Janssen Biotech 26
3.8 Comparative Efficacy and Safety 28
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4 Psoriasis Market to 2021-Pipeline Products 29
4.1 Overview 29
4.2 Overall Pipeline 29
4.3 Pipeline Analysis by Molecule Type 31
4.4 Pipeline Analysis by Molecular Target 32
4.5 Clinical Trials 34
4.5.1 Overall Failure Rate 34
4.5.2 Failure Rate by Molecule Type 35
4.5.3 Failure Rate by Molecular Target 36
4.5.4 Patient Enrollment and Clinical Trial Size 37
4.5.5 Duration 38
4.5.6 Summary of Psoriasis Clinical Trials 39
4.6 Promising Drug Candidates in the Pipeline 40
4.6.1 LY2439821 (ixekizumab)-Eli Lilly 40
4.6.2 Xeljanz (tofacitinib)-Pfizer 41
4.6.3 Brodalumab-Amgen 42
5 Market Forecast to 2021 44
5.1 Geographical Markets 44
5.1.1 Asia-Pacific Market Overview 44
5.1.2 China 46
5.1.3 India 49
5.1.4 Japan 51
5.1.5 Australia 53
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