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Amgen and Arrowhead to develop gene-therapies for heart disease
29 Sep 2016 at 4:47am
(Reuters) - Amgen Inc said on Thursday it would buy a stake in Arrowhead Pharmaceuticals Inc and team up with the company to develop gene-silencing therapies for heart disease. Pasadena, California-based Arrowhead will get $35 million up front and will be eligible to receive up to $617 million in milestone payments. It will also get $21.5 million from Amgen through an equity investment.
'Cancer hotels' house China's patient refugees
29 Sep 2016 at 4:44am
By Kim Kyung Hoon BEIJING (Reuters) - In the shadow of one of China's top cancer hospitals in Beijing, a catacomb-like network of ramshackle brick buildings has become a home-from-home for hundreds of cancer patients and their families waiting for treatment. The cluster of nine buildings, connected by dark, narrow passageways, offers cheap accommodation for patients unable to afford a coveted hospital room, a reflection of the vast inequalities in China's overburdened healthcare system. Good doctors don't want to work in small places," said Liu, 46, a migrant worker who brought his wife more than 750 km (450 miles) to see a specialist in the capital in May. His wife, Wang, 42, was diagnosed with cervical cancer at the beginning of the year, and was told by family she should leave her hometown in Inner Mongolia for treatment.
Colombia tipped for Nobel Peace Prize after deal to end war
29 Sep 2016 at 4:16am
By Alister Doyle and Jessica Jaganathan OSLO (Reuters) - A Colombian peace accord ending a half-century of war is widely tipped for the Nobel Peace Prize next week, returning the award to its roots after a run of wins for organizations including the European Union. The prize might be shared by President Juan Manuel Santos and Marxist FARC rebel leader Timochenko - the nom de guerre of Rodrigo Londono - after they signed a deal on Sept. 26 to end a war that killed a quarter of a million people. "The agreement ... is one of the most obvious peace prize candidates I've ever seen," said Asle Sveen, a historian who tracks the awards.
Schedule of Nobel Prize 2016 announcements
29 Sep 2016 at 4:15am
STOCKHOLM (Reuters) - Sweden's annual crop of Nobel Prizes for achievements in science, literature and peace is announced in the coming days, beginning with the medicine prize. Oct. 3 Nobel Prize in Physiology or Medicine (announced in Stockholm at 0930 GMT at the earliest) Oct. 4 Nobel Prize in Physics (announced in Stockholm at 0945 GMT at the earliest) Oct. 5 Nobel Prize in Chemistry (announced in Stockholm at 0945 GMT at the earliest) Oct. 6 (possible date) Nobel Prize in Literature (according to tradition, the exact date for this prize is only announced shortly before it is presented. ...
Japan conglomerates seek to merge loss-making nuclear fuel operations: sources
29 Sep 2016 at 3:19am
Three Japanese conglomerates are in talks to combine their loss-making domestic nuclear fuel operations, people with direct knowledge of the matter said, as the outlook for restarts of reactors following the Fukushima nuclear crisis remains bleak. Hitachi Ltd , Toshiba Corp and Mitsubishi Heavy Industries Ltd aim to merge the operations as early as spring 2017, one of the people said, declining to be identified as the discussions were confidential. The person added that the three companies may eventually consider merging their nuclear reactor businesses, although nothing specific has been discussed so far.
California shooting shows police ill-equipped to handle mentally ill
29 Sep 2016 at 3:03am
Alfred Olango, 38, a Ugandan-born immigrant, was shot by one officer even as another, who had been trained to deal with mentally ill people, attempted to subdue him with a Taser, police said. The confrontation in the San Diego suburb of El Cajon came at a time when San Diego County is facing a doubling of mental health-related calls since 2009, officials said, tracking the impact of decades of tight budgets for mental health services. "This is a systemic issue across the country," said Maggie Merritt, executive director of the Steinberg Institute, a mental health policy research and advocacy group in Sacramento.
Painkillers linked to heart failure: study
29 Sep 2016 at 1:52am
Widely used prescription and non-prescription painkillers are associated with an increased risk of hospital admission for heart failure, according to a study released Thursday. The drugs in question are so-called NSAIDs, or non-steroidal anti-inflammatory drugs, including several known as COX-2 inhibitors. The broad link between the use of NSAIDs and heart failure is well established, but which drugs pose the greatest risk, and at what doses, remains poorly understood.
Utah man may have contracted Zika from dying father's tears
29 Sep 2016 at 1:32am
SALT LAKE CITY (AP) ? A Utah man who mysteriously contracted Zika from his infected father may have got it by touching his dad's tears or sweat with his bare hands, according to new research that found the unusual transmission method was likely caused by his dying father having 100,000 times the normal level of the virus.
Novo Nordisk to ax 1,000 jobs in cost-cutting drive
29 Sep 2016 at 12:43am
The world's largest insulin maker, Novo Nordisk, is cutting 1,000 jobs as a part of a plan to reduce costs as it faces a challenging environment in 2017, especially in the large U.S. market, the company said on Thursday. "We have concluded that it is needed in order for us to have a sustainable balance between income and costs," Chief Executive Lars Rebien Sorensen said in a statement.
Did landmark laws from Congress enable high drug prices?
29 Sep 2016 at 12:27am
WASHINGTON (AP) ? Lawmakers are venting outrage over high prescription drug costs, but if Congress is looking for culprits, it might want to look in the mirror.
Novo Nordisk to axe 1,000 jobs in cost-cutting drive
29 Sep 2016 at 12:19am
The world's largest insulin maker, Novo Nordisk , is cutting 1,000 jobs as a part of a plan to reduce costs as it faces a challenging environment in 2017, especially in the large U.S. market, the company said on Thursday. "We have concluded that it is needed in order for us to have a sustainable balance between income and costs," Chief Executive Lars Rebien Sorensen said in a statement.
Scientists fix fractures with 3D-printed synthetic bone
28 Sep 2016 at 11:50pm
By Kate Kelland LONDON (Reuters) - Scientists in the United States have successfully treated broken spines and skulls in animals using 3D-printed synthetic bone, opening the possibility of future personalized bone implants for humans to fix dental, spinal other bone injuries. Unlike real bone grafts, the synthetic material - called hyper-elastic bone - is able to regenerate bone without the need for added growth factors, is flexible and strong, and can be easily and rapidly deployed in the operating room. Giving details in a teleconference, the scientists said the results of their animal trials - published on Wednesday in the Science Translational Medicine journal - were "quite astounding".
Investigators search for clues in South Carolina school shooting
28 Sep 2016 at 11:11pm
Investigators were searching on Thursday for the motive behind a shooting spree by a South Carolina teenager who killed his father and wounded two school students and a teacher before being pinned down by a volunteer fireman. The 14-year-old boy, whose name has not been released, shot and killed his father, Jeffrey DeWitt Osborne, 47, on Wednesday afternoon. Then he drove to Townville Elementary School, where he shot two boys and a woman teacher with a handgun, before being subdued by the volunteer firefighter, police said.
Actelion to investigate all-oral MS combination therapy
28 Sep 2016 at 10:16pm
ZURICH (Reuters) - Swiss biotech group Actelion Ltd will investigate an all-oral combination therapy for patients with relapsing multiple sclerosis (RMS), it said, calling it the first study of this approach for treating the neurological disorder. It said it would study combining ponesimod and dimethyl fumarate (Tecfidera) for patients with RMS. The POINT study will be conducted under a Special Protocol Assessment agreement with the U.S. Food and Drug Administration. ...
The cost of cheap drugs? Toxic Indian lake is 'superbug hotspot'
28 Sep 2016 at 10:14pm
By Zeba Siddiqui HYDERABAD, India (Reuters) - Centuries ago, Indian princes would bathe in the cool Kazhipally lake in Medak. Now, even the poorest villagers here in India's baking south point to the barren banks and frothy water and say they avoid going anywhere near it. A short drive from the bustling tech hub of Hyderabad, Medak is the heart of India's antibiotics manufacturing business: a district of about 2.5 million that has become one of the world's largest suppliers of cheap drugs to most markets, including the United States.